Illnesses in siblings of US patients with bipolar disorder relate to multigenerational family history and patients severity of illness
详细信息 查看全文
- 作者：Robert M. Posta ; b ; ; Lori L. Altshulerc ; d ; Ralph Kupkae ; Susan L. McElroyf ; g ; Mark A. Fryeh ; Michael Rowea ; Heinz Grunzei ; Trisha Suppesj ; k ; Paul E. Keck Jre ; f ; Willem A. Nolenl
- 关键词：Depression ; Alcohol abuse/dependence ; Substance abuse/dependence ; Suicide attempts ; Anxiety disorder ; Transgenerational vulnerability ; Illness differences across countries
- 刊名：Journal of Affective Disorders
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：207
- 期：Complete
- 页码：313-319
- 全文大小：395 K
文摘
- •
Compared to Europeans, siblings of bipolar patients from the US are more ill.
- •
Positive family history of psychiatric problems breeds true into the siblings.
- •
Adverse characteristics in bipolar patients predict psychiatric problems in siblings.
- •
Multigenerational family burden in the US suggests the need for new interventions.