Exposure Factor considerations for safety evaluation of modern disposable diapers

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• 作者：Swatee Dey^a ; ^{dey.s.3@pg.com} ; Mike Purdon^a ; Taryn Kirsch^b ; HansMartin Helbich^b ; Kenny Kerr^a ; Lijuan Li^a ; Shaoying Zhou^a
• 关键词：Baby ; Exposure based safety assessment ; Disposable baby diapers ; Exposure ; Diaper safety ; Children
• 刊名：Regulatory Toxicology and Pharmacology
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：81
• 期：Complete
• 页码：183-193
• 全文大小：1155 K
• 卷排序：81

文摘

Disposable diapers are 3D products with varied ‘in use’ constituent exposure scenarios. Understanding habits and practices of diapers is critical for a robust exposure based safety assessment. Average diaper frequency of use is 4.7 per day. Default direct and indirect skin contact constituent transfer is 3–4.3% and 0.32–0.66% respectively.