Intraoperative assessment of sentinel lymph node by one-step nucleic acid amplification in breast cancer patients after neoadjuvant treatment reduces the need for a second surgery for axillary lymph node dissection
OSNA detect positives SLNs after NAC as accurately as conventional pathology. The false negative rate of FS after NAC was 18.5% with a sensitivity of 81.5%. Intraoperative definitive assessment by OSNA reduces the need for a second surgery.