Enhanced stability and solubility of pH-dependent drug, telmisartan achieved by solid dispersion

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• 作者：Jin-Seok Choi ^{c34281@gmail.com}
• 关键词：Telmisartan (TLM) ; Solid dispersion (SD) ; Meglumine ; Dissolution rate ; Stability
• 刊名：Journal of Drug Delivery Science and Technology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：37
• 期：Complete
• 页码：194-203
• 全文大小：1417 K
• 卷排序：37

文摘

TLM-SD was prepared with meglumine and PVP K30 by melting and solvent evaporation method. Enhanced the solubility and dissolution rate of TLM-SD. First attempt to the hygroscopic test for Telmisartan tablets.