Mapping the dynamics of cortical neuroplasticity of skilled motor learning using micro X-ray fluorescence and histofluorescence imaging of zinc in the rat

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• 作者：Mariam Alaverdashvili^a ; ^b ; ^c ; ^{mariam.alaverdashvili@usask.ca} ; Phyllis G. Paterson^a ; ^b
• 关键词：Skilled motor learning ; Neural plasticity ; Neural efficiency ; Synchrotron ; Micro X-ray fluorescence imaging ; Zinc
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：318
• 期：Complete
• 页码：52-60
• 全文大小：1239 K
• 卷排序：318

文摘

Moderate and distributed practice in skilled reaching promotes neural plasticity. c-Fos upregulation parallels the improved proficiency in skilled forelimb use. Gluzinergic neurons may contribute to maintenance of the learned motor skills. μXFI of cortical Zn doesn’t detect neural plasticity after skilled motor learning. Multimodal imaging should be applied to studies on post-stroke brain plasticity.