Enzyme-polymer hybrid nanogels fabricated by thiol-disulfide exchange reaction
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- 作者：Xiaotian Jia ; Jinchuan Liua ; Li Liua ; nkliuli@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Hanying Zhaoa ; b ; hyzhao@nankai.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hybrid nanogels ; Thiol-disulfide reaction ; Porcine pancreatic lipase ; LCST ; Bioactivity
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 December 2016
- 年：2016
- 卷：148
- 期：Complete
- 页码：41-48
- 全文大小：2498 K
文摘
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Enzyme-polymer nanogels are prepared by thiol-disulfide exchange reactions.
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Morphology changes at different temperatures are investigated.
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The hybrid nanogels show thermal responsiveness, and LCSTs are determined.
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Enzyme molecules immobilized on the nanogels show enhanced heat resistance.