Effects of fullerenol nanoparticles and amifostine on radiation-induced tissue damages: Histopathological analysis
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- 作者：Jacevic Vesnaa ; b ; c ; Jovic Danicad ; Kuca Kamilc ; e ; kamil.kuca@fnhk.cz" class="auth_mail" title="E-mail the corresponding author ; ; Dragojevic-Simic Viktorijab ; f ; Dobric Silvab ; g ; Trajkovic Sanjah ; Borisev Ivanac ; Segrt Zoranb ; i ; Milovanovic Zorana ; Bokonjic Dubravkob ; Djordjevic Aleksandarc
- 关键词：X-ray radiation ; Tissue damages ; Radioprotection ; Fullerenol nanoparticles ; Amifostine
- 刊名：Journal of Applied Biomedicine
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：14
- 期：4
- 页码：285-297
- 全文大小：3233 K
文摘
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Monitoring acute toxicity of fullerenol and amifostine in rats irradiated by X-rays.
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Assessment antiinflammatory activity of radioprotectors by tissue damage score.
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Amifostine (300 mg/kg) expressed better radioprotection of heart, liver and kidney.
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Fullerenol (100 mg/kg) is better radioprotector of small intestine, lung and spleen.