Cadmium-induced oxidative damages in the human BJAB cells correlate with changes in intracellular trace elements levels and zinc transporters expression
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- 作者：Saï ; d Nemmichea ; snemiche@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Pascale Guiraudb
- 关键词：Zip ; Zrt- and Irt-like (SLC39A) proteins ; ZnT ; solute-linked carrier 30 (SLC30A) proteins ; DMT1 ; divalent metal-ion transporter 1 ; MTF1 ; metal-responsive transcription factor 1 ; MT ; Metallothionein ; MRE ; metal response element ; 8-OHdG ; 8-Oxo-deoxyguanosine
- 刊名：Toxicology in Vitro
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：37
- 期：Complete
- 页码：169-177
- 全文大小：882 K
文摘
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Cd induces formation of 8-OHDG adducts and augmented MTF1 expression in BJAB cells.
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Cd exposure causes change in expression of ZnTs and Zips transporters.
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Cd exposure increased the expression of DMT1 and caused an up-regulation of ZnT1.
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The T calcium channel alpha1G subunit could not be detected.