- 作者：Daniel Rodr¨ªguez ; Francesc Formiga ; Isabel Fort ; Mar¨ªa Jos¨¦ Robles ; Elena Barranco ; Dolors Cub¨ª ; en representaci¨®n del grupo de Trabajo de Demencias de la Sociedad Catalana de Geriatr¨ªa y Gerontolog¨ªa
- 关键词：Tratamiento farmacoló ; gico ; Demencia ; Inhibidores de la acetil colinesterasa ; Memantina
- 刊名：Revista Espa?ola de Geriatr¨ªa y Gerontolog¨ªa
- 出版年：2012
- 出版时间：September-October, 2012
- 年：2012
- 卷：47
- 期：5
- 页码：228-233
- 全文大小：264 K
Dementia in general ?and Alzheimer's disease (AD) in particular? are bound to loom large among the most acute healthcare, social, and public health problems of the 21st century. AD shows a degenerative progression that can be slowed down ?yet not halted? by today's most widely accepted specific treatments (those based on cholinesterase inhibitors as well as those using memantine). There is enough evidence to consider these treatments advisable for the mild, moderate and severe phases of the illness. However, in the final stage of the disease, a decision has to be made on whether to withdraw such treatment or not. In this paper, the Working Group on Dementia for the Catalan Society of Geriatrics and Gerontology reviews the use of these specific pharmacological treatments for AD, and, drawing on the scientific evidence thus gathered, makes a series of recommendations on when, how, and for how long, the currently existing specific pharmacological treatments should be used.