Effectiveness of the MF59-adjuvanted influenza vaccine in preventing emergency admissions for pneumonia in the elderly over 64 years of age
详细信息 查看全文
- 作者：Puig-Barberà ; Joan ; Diez-Domingo ; Javier ; Pé ; rez Hoyos ; Santiago ; Belenguer Varea ; Á ; ngel ; et. al.
- 关键词：MF59-adjuvanted influenza vaccine ; Pneumonia ; Elderly
- 刊名：Vaccine
- 出版年：2004
- 出版时间：December 2, 2004
- 年：2004
- 卷：23
- 期：3
- 页码：283-289
- 全文大小：165 K
文摘
Case–control study designed to determine the effectiveness of an MF59-adjuvanted influenza vaccine in the population aged 65 years and older living in the community. Detailed health histories were obtained on both cases and controls that included a functional measure of co-morbidity (Barthel Index). Subjects were all eligible persons admitted to various hospitals with a diagnosis of pneumonia during the winter months and were matched by sex, hospital and admission week to controls admitted for non-medical reasons. The influenza vaccination programme using the MF59-adjuvanted influenza vaccine significantly reduced the probability of being hospitalised for pneumonia in the elderly over 64 years of age, even in a season with a low influenza activity, during which the predominant circulating strains were types B and A (H1N1).