Seroepidemiological surveillance of Burkholderia pseudomallei in Bangladesh

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• 作者：Rapeephan R. Maude ; Richard J. Maude ; Aniruddha Ghose ; Md Robed Amin ; Md Belalul Islam ; Mohammad Ali ; Md Shafiqul Bari ; Md Ishaque Majumder ; Vanaporn Wuthiekanan ; Arjen M. Dondorp ; Robin L. Bailey ; Nicholas P.J. Day ; M. Abul Faiz
• 关键词：Burkholderia pseudomallei ; Melioidosis ; Indirect haemagglutination assay ; Seroprevalence ; Epidemiological surveillance ; Bangladesh
• 刊名：Transactions of the Royal Society of Tropical Medicine and Hygiene
• 出版年：2012
• 出版时间：September, 2012
• 年：2012
• 卷：106
• 期：9
• 页码：576-578
• 全文大小：141 K

文摘

Melioidosis (m>Burkholderia pseudomalleim> infection) has yet to be demonstrated systematically in Bangladesh. A prospective, cross-sectional serological survey was conducted in 2010 at six Bangladeshi hospitals. Age, gender, occupation and residential address were recorded. Of 1244 patients, 359 (28.9 % ) were positive for m>B. pseudomalleim> by indirect haemagglutination assay. Farmers had an increased risk of seropositivity (risk ratio = 1.4, 95 % CI 1.0-1.8; p = 0.03). There was no clear geographic clustering of seropositives. Melioidosis should be considered as a possible cause of febrile illness in Bangladesh. Further studies are needed to establish the incidence of clinical disease and distribution of environmental risk.