The prevalence, clinical correlates and structure of phobic fears in Han Chinese women with recurrent major depression

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• 作者：Fuzhong Yang^a ; Jianyin Qiu^a ; Hongsu Zhao^b ; Zhoubing Wang^c ; Danhong Tao^d ; Xue Xiao^e ; Qihui Niu^f ; Qian Wang^g ; Yajuan Li^h ; Liyang Guoⁱ ; Jianying Li^j ; Kan Li^k ; Jing Xia^l ; Lina Wang^m ; Xiaofang Shangⁿ ; Wenhua Sang^o ; Zhaoyu Gan^p ; Kangmei He^q ; Xiaochuan Zhao^r ; Tian Tian^s ; Dan Xu^t ; Danhua Gu^u ; Xiaoqin Weng^v ; Haimin Li^w ; Jing Tian^x ; Lijun Yang^y ; Qiang Li^z ; Qingzhen Yang^aa ; Hui Wang^ab ; Yamei Dang^ac ; Lei Dai^ad ; Yanping Cui^ae ; Dong Ye^af ; Juling Cao^ag ; Li Guo^ah ; Zhen Kang^ai ; Jimeng Liu^aj ; Bin Chen^ak ; Jinhua Liu^al ; Jinling Zhang^am ; Donglin Yang^an ; Bin Jiao^ao ; Fengyu Yu^ap ; Feng Geng^aq ; Ling Li^ar ; Haiying Yang^as ; Hong Dai^at ; Hongli Wang^au ; Caixing Liu^a ; v ; Haijun Liu^aw ; Longyan Peng^ax ; Xiaoping Wang^ay ; Shaojun Wei^az ; Xiaojuan Liu^bb ; Chang Li^bc ; Zhengrong Liu^bd ; Qiwen Zhang^be ; Dongchuan Di^bf ; Shenxun Shi^bg ; Jonathan Flint^bh ; Kenneth S. Kendler^bi ; ^{kendler@vcu.edu" class="auth_mail}
• 关键词：Phobic fear ; Major depression ; Prevalence ; Comorbidity ; Factor analysis
• 刊名：Journal of Affective Disorders
• 出版年：20 March, 2014
• 年：2014
• 卷：157
• 期：Complete
• 页码：92-99
• 全文大小：358 K

文摘

Background

Phobic fears are common in the general population and among individuals with major depression (MD). We know little about the prevalence, clinical correlates, and structure of phobic fears in Chinese women with MD.

Methods

We assessed 22 phobic fears in 6017 Han Chinese women with MD. We used exploratory factor analysis to examine the structure of these phobic fears. We examined the relationship between individual phobic fears and the severity of MD, neuroticism, comorbid panic disorder, generalized anxiety disorder and dysthymia using logistic regression models.

Results

The frequency of phobic fears ranged from 3.0% (eating in public) to 36.0% (snakes). Phobic fears were significantly associated with more severe MD, high neuroticism, and co-morbid panic disorder, generalized anxiety disorder and dysthymia. Our factor analysis suggested four underlying subgroups of phobic fears which differed in their clinical correlates, severity and patterns of comorbidity.

Limitations

Data were collected retrospectively through interview and recall bias may have affected the results.

Conclusions

Phobic fears are correlated with comorbid MD and more severe MD. These phobic fears clearly subdivide into four subgroups that differ meaningfully from each other.