Dynamic changes in CD45RA∿/sup>Foxp3high regulatory T-cells in chronic hepatitis C patients during antiviral therapy
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- 作者：Zhiqin Lia ; b ; 1 ; Yu Pingb ; c ; 1 ; Zujiang Yua ; Meng Wangb ; Dongli Yueb ; Zhen Zhangb ; Jianbin Lid ; Bin Zhangb ; e ; Xuezhong Shif ; xzshi@zzu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yi Zhangb ; c ; g ; yizhang@zzu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Treg cells ; HCV antiviral therapy ; IFN-α ; Ribavirin
- 刊名：International Journal of Infectious Diseases
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：45
- 期：Complete
- 页码：5-12
- 全文大小：2086 K
文摘
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Activated regulatory T-cells (aTreg cells) were found to express high levels of CD39, CD73, and transforming growth factor beta (TGF-β).
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Total Treg cells and aTreg cells decreased during antiviral therapy.
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Targeting aTreg might be a future solution to prevent relapse of chronic hepatitis C.