Gene expression profiling reveals different molecular patterns in G-protein coupled receptor signaling pathways between early- and late-onset preeclampsia
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- 作者：Mengmeng Lianga ; Jianmin Niua ; njianmin@163.com" class="auth_mail" title="E-mail the corresponding author ; Liang Zhangb ; Liang_zhang_71@qq.com" class="auth_mail" title="E-mail the corresponding author ; Hua Dengb ; Jian Mab ; Weiping Zhoub ; Dongmei Duana ; Yuheng Zhoua ; Huikun Xua ; Longding Chena
- 关键词：Early-onset preeclampsia ; Late-onset preeclampsia ; Microarray ; G-protein coupled receptor signaling pathway
- 刊名：Placenta
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：40
- 期：Complete
- 页码：52-59
- 全文大小：935 K
文摘
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The gene expression profiles between early- and late-onset preeclampsia were different.
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Our results supported the hypothesis that they are separate disease entities.
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The development of late-onset PE associated with minor placental involvement.
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G-protein coupled receptors may contribute to the mechanism of early-onset PE.