Computational study of the fluid-dynamics in carotids before and after endarterectomy

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• 作者：Bruno Guerciotti^a ; Christian Vergara^b ; ^{christian.vergara@polimi.it" class="auth_mail" title="E-mail the corresponding author} ; Laura Azzimonti^c ; Laura Forzenigo^d ; Adelaide Buora^e ; ^f ; Piero Biondetti^d ; Maurizio Domanin^e ; ^f
• 关键词：Endarterectomy ; CFD ; Restenosis ; Carotids
• 刊名：Journal of Biomechanics
• 出版年：2016
• 出版时间：4 January 2016
• 年：2016
• 卷：49
• 期：1
• 页码：26-38
• 全文大小：8644 K

文摘

In this work, we provide a computational study of the effects of carotid endarterectomy (CEA) on the fluid-dynamics at internal carotid bifurcations. We perform numerical simulations in real geometries of the same patients before and after CEA, using patient-specific boundary data obtained by Echo-Color Doppler measurements. We analyze four patients with a primary closure and other four where a patch was used to close arteriotomies. The results show that (i) CEA is able to restore physiological fluid-dynamic conditions; (ii) among the post-operative cases, the presence of patch leads to local hemodynamic conditions which might imply a higher risk of restenosis in comparison with the cases without patch.