The use of a restricted access volatile supramolecular solvent for the LC/MS-MS assay of bisphenol A in urine with a significant reduction of phospholipid-based matrix effects
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- 作者：José ; Á ; ngel Salatti-Dorado ; Noelia Caballero-Casero ; Marí ; a Dolores Sicilia ; Marí ; a Loreto Lunar ; Soledad Rubio ; qa1rubrs@uco.es
- 关键词：Supramolecular solvent-based microextraction ; Liquid chromatography/tandem mass spectrometry ; Urine samples ; Protein/phospholipid removal ; Bisphenol A
- 刊名：Analytica Chimica Acta
- 出版年：2017
- 出版时间：15 January 2017
- 年：2017
- 卷：950
- 期：Complete
- 页码：71-79
- 全文大小：1409 K
- 卷排序：950
文摘
A sample treatment platform is designed for matrix-effect removal in LC-MS bioanalysis It is based on the use of restricted access-volatile supramolecular solvents. Proteins and phospholipids are removed from biological samples by precipitation. Removal of ionization suppression is proved for quantification of BPA in urine by LC-(ESI)MS/MS.