Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
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- 作者：Kai Kretzschmar1 ; 2 ; 3 ; 5 ; Christine Weber1 ; 3 ; Ryan R. Driskell1 ; Eduardo Calonje4 ; Fiona M. Watt1 ; fiona.watt@kcl.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：12 January 2016
- 年：2016
- 卷：14
- 期：2
- 页码：269-281
- 全文大小：6632 K
文摘
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LGR6+ and LRIG1+ stem cells give rise to β-catenin-induced hair follicles
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LGR6 defines stem cells of tail interscale interfollicular epidermis
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β-Catenin activation in different stem cells induces distinct tumor types
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Different β-catenin-induced tumors differ in stromal composition