Strain-specific Plasmodium falciparum multifunctional CD4+ T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate
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- 作者：Shawna F. Gravesa ; Bourema Kouribab ; Issa Diarrab ; Modibo Daoub ; Amadou Niangalyb ; Drissa Coulibalyb ; Yamoussa Keitab ; Matthew B. Laurensa ; c ; Andrea A. Berrya ; c ; Johan Vekemansd ; W. Ripley Balloud ; David E. Lanare ; Sheetij Duttae ; D. Gray Heppnere ; Lorraine Soissonf ; Carter L. Diggsf ; Mahamadou A. Therab ; Ogobara K. Doumbob ; Christopher V. Plowea ; c ; Marcelo B. Szteina ; Kirsten E. Lykea ; klyke@medicine.umaryland.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Malaria ; Pediatric ; T cell ; Multifunctional ; AMA1 ; FMP2.1/AS02A
- 刊名：Vaccine
- 出版年：2016
- 出版时间：17 May 2016
- 年：2016
- 卷：34
- 期：23
- 页码：2546-2555
- 全文大小：1261 K
文摘
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We demonstrate an AMA1-specific T cell response following vaccination.
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The antigen-specific immune response was detectable in an at-risk population in Mali.
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A differential pediatric immune response with clinical malaria vaccinees is shown.