Beijing clades of Mycobacterium tuberculosis are associated with differential survival in HIV-negative Russian patients
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- 作者：Yanina Balabanovaa ; b ; c ; 1 ; yanina.lenz@imperial.ac.uk" class="auth_mail" title="E-mail the corresponding author ; LenzY@rki.de" class="auth_mail" title="E-mail the corresponding author ; Vladyslav Nikolayevskyya ; b ; 1 ; Olga Ignatyevad ; Irina Kontsevayad ; Svetlana Mironovad ; Alexander Kovalyovd ; Andrey Kritskyd ; Yulia Rodionovad ; Ivan Fedorind ; Nicola Casalib ; Richard Hoopere ; Rolf D. Horstmannf ; Sergey Nejentsevg ; Sven Hoffnerh ; Peter Nuernbergi ; Francis Drobniewskia ; b
- 关键词：Tuberculosis ; Beijing family of strains ; Clades ; Survival ; Russia
- 刊名：Infection, Genetics and Evolution
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：36
- 期：Complete
- 页码：517-523
- 全文大小：519 K
文摘
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Two highly homogenous M.tuberculosis Beijing clades dominate in Samara Oblast, Russia.
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Tuberculosis caused by dominant Beijing clades was associated with poorer survival.
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MDR and XDR significantly decrease survival of TB patients.
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Differential patient survival occurred with Beijing strains independent of drug resistance.
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Social vulnerability and extensive diseases decrease survival in HIV-negative TB patients.