Arabino mycolates from synthetic mycolic acids

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• 作者：Mohsin O. Mohammed^&dagger ; ; Mark S. Baird ; ^{chs028@bangor.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Juma'a R. Al Dulayymi ; Alison Jones ; Christopher D. Gwenin
• 关键词：Mycobacteria ; Tuberculosis ; Arabino mycolates ; Antigens
• 刊名：Tetrahedron
• 出版年：2016
• 出版时间：2 June 2016
• 年：2016
• 卷：72
• 期：22
• 页码：2849-2857
• 全文大小：456 K

文摘

The synthesis of single mono-arabino mycolates, important lipid antigens from mycobacteria is described, using structurally defined synthetic mycolic acids. Preliminary assays indicate that these are differentially antigenic to antibodies in the serum of people with active tuberculosis.