Apolipoprotein E levels and apolipoprotein E genotypes in incident cardiovascular disease risk in subjects of the Prevention of Renal and Vascular End-stage disease study
详细信息 查看全文
- 作者：James P. Corsetti ; MD ; PhD
- 关键词：Apolipoprotein E ; Cardiovascular disease ; Lipoproteins ; Apolipoprotein E polymorphism ; Apolipoprotein B
- 刊名：Journal of Clinical Lipidology
- 出版年：2016
- 出版时间：July-August 2016
- 年：2016
- 卷：10
- 期：4
- 页码：842-850
- 全文大小：278 K
文摘
- •
- <p id="p0010">ApoE is a component of all major lipoprotein classes.p>
- •
- <p id="p0015">ApoE has multiple functions in lipoprotein metabolism especially atherogenesis.p>
- •
- <p id="p0020">Many studies are published on apoE genotypes and risk but few on apoE levels and risk.p>
- •
- <p id="p0025">Results demonstrate association of apoE levels on risk independent of apoE genotype.p>
- •
- <p id="p0030">ApoE-associated risk likely derives from apoB lipoproteins enriched with apoE.p>