Do social functioning and symptoms improve with continuation antidepressant treatment of persistent depressive disorder? An observational study

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• 作者：David J. Hellerstein^a ; ^b ; ^{hellers@nyspi.columbia.edu} ; Kallio Hunnicutt-Ferguson^c ; Jonathan W. Stewart^a ; ^b ; Patrick J. McGrath^a ; ^b ; Samantha Keller^a ; Bradley S. Peterson^d ; Ying Chen^a ; ^b
• 关键词：Dysthymic disorder ; Persistent depressive disorder ; Maintenance treatment ; Psychosocial functioning ; Psychopharmacology ; Serotonin norepinephrine reuptake inhibitor ; Duloxetine
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：1 March 2017
• 年：2017
• 卷：210
• 期：Complete
• 页码：258-264
• 全文大小：362 K
• 卷排序：210

文摘

Continued duloxetine treatment appears to maintain symptom response in dysthymic disorder, and improves social functioning. However, the majority of patients do not show normalization of functioning, even when controlling for remission status. Additional treatments should be considered to target residual social impairment in mood remitted persistent depression.