Solid phase synthesis of aminoboronic acids: potent inhibitors of the hepatitis C virus NS3 proteinase

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• 作者：Dunsdon ; Rachel M. ; Greening ; John R. ; Jones ; Philip S. ; Jordan ; Steven ; Wilson ; Francis X.
• 刊名：Bioorganic and Medicinal Chemistry Letters
• 出版年：2000
• 出版时间：July 17, 2000
• 年：2000
• 卷：10
• 期：14
• 页码：1577-1579
• 全文大小：142 K

文摘

Use of a resin bound diol as a boronic acid protecting group has been developed to allow the parallel synthesis of potent inhibitors of the hepatitis C virus NS3 serine proteinase.