Pigmented renal clear cell carcinoma with melanocytic differentiation

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• 作者：Jun-Yi Lei ; Lavinia P. Middleton ; Xiao-Du Guo ; Paul H. Duray ; Glen McWilliams ; W. Marston Linehan ; Maria J. Merino
• 刊名：Human Pathology
• 出版年：2001
• 出版时间：February 2001
• 年：2001
• 卷：32
• 期：2
• 页码：233-236
• 全文大小：285 K

文摘

Renal cell carcinoma (RCC) is the most common malignant tumor of the adult kidney, and its incidence has been steadily rising. RCC consists of several subtypes, each of which has its own clinical features, and cytogenetic and molecular characteristics. Recognizing histologic patterns of RCC is important not only for correct diagnosis, but also for providing insight into the biological behavior of the tumor and subsequent appropriate medical care for the patient. Pigments other than hemosiderin has been observed in RCC, but none of them have been proved to be melanin. Melanotic tumors, either primary or metastatic, are rare in the kidney. We present an unusual case of melanin-pigmented clear cell RCC with melanocytic differentiation, an unusual variant that may lead to errors in diagnosis and treatment. H P 32:233-236. This is a US Government work. There are no restrictions on its use.