Observational study. A total of 274 physicians, working in a teaching hospital in Paris, France were asked to answer a questionnaire including four vignettes presenting the results of a therapeutic, a diagnostic, a prognostic study and a meta-analysis of clinical trials.
A total of 130 (47 % ) questionnaires were returned. We observed the highest proportion of good answers for questions about absolute risk reduction (87.7 % ), sensitivity (84.6 % ), and specificity (80 % ); and the lowest for the calculation and use of the likelihood ratio (16.9 % and 9.2 % , respectively). The global mean score was 5.0/10 (95 % confidence interval = 4.6–5.4, range 0–9.4). Physicians got higher scores for questions related to treatment than for questions related to diagnosis: mean scores 7.1 (6.6–7.6) vs. 4.2 (3.8–4.6). Regression analysis did not reveal any significant relationship between global performance and physicians' age (r2 = 0.002, not significant [NS])
Physicians demonstrated only moderate knowledge and usage of clinical epidemiology terms used in major medical journals. Their capacity to interpret quantitative data from medical scientific literature may be limited.