Effect of remifentanil and fentanyl on postoperative cognitive function and cytokines level in elderly patients undergoing major abdominal surgery
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- 作者：Germano De Cosmo ; MDa ; gdecosmo@rm.unicatt.it" class="auth_mail" title="E-mail the corresponding author (Associate Professor ; Director) ; Flaminio Sessa ; MDb (Resident) ; Federico Fiorini ; MDb (Resident) ; Elisabetta Congedo ; MD ; PhDc (Attending Physician)
- 关键词：Remifentanil ; Fentanyl ; Post operative cognitive dysfunction ; Analgesia ; Cytokines
- 刊名：Journal of Clinical Anesthesia
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：40-46
- 全文大小：289 K
文摘
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POCD in elderly patients is a relevant problem in major abdominal surgery.
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There is no difference between fentanyl and remifentanil in term of POCD.
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Patients who had received remifentanil showed lower values of IL-6.
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Correlation between remifentanil and its anti-inflammatory effect is not reached.