Cetuximab activity in dysplastic lesions of the upper aerodigestive tract
详细信息 查看全文
- 作者：Zubair Khana ; Joel B. Epsteine ; 1 ; Shanthi Marurb ; M. Boyd Gillespief ; Lawrence Feldmane ; Hua-Ling Tsaia ; Zhe Zhangc ; Hao Wangc ; James Sciubbad ; Robert Ferrisg ; Jennifer R. Grandisg ; Michael Gibsong ; Wayne Kocha ; Ralph Tufanoa ; William Westrab ; Nancy Tsottlesb ; Hiroyuki Ozawab ; Christine Chungb ; Joseph A. Califanoa ; d ; jcalifano@ucsd.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Oral dysplasia ; Head and neck cancer ; Head and neck premalignancy
- 刊名：Oral Oncology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：53
- 期：Complete
- 页码：60-66
- 全文大小：638 K
文摘
- •
Clinical trial to determine effects of cetuximab on high risk oral premalignancy.
- •
Patients with mild, moderate, severe head and neck dysplasia enrolled.
- •
Primary objective to determine histologic response to treatment with cetuximab.
- •
Cetuximab may result in histological resolution in at least a subset of patients.