Antibody Levels against α-Galactosyl Epitopes in Sera of Patients with Squamous Intraepithelial Lesions and Early Invasive Cervical Carcinoma

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• 作者：Tremont-Lukats ; Ivo W. ; Avila ; Jos&eacute ; L. ; Herná ; ndez ; Dimas ; Vá ; squez ; Jesú ; s ; et. al.
• 刊名：Gynecologic Oncology
• 出版年：1997
• 出版时间：February, 1997
• 年：1997
• 卷：64
• 期：2
• 页码：207-212
• 全文大小：102 K

文摘

We measured serum levels of anti-Gal(α1 → 3)Gal and anti-Gal(α1 → 2)Gal antibodies in 89 and 91 women, respectively, by using ELISA. These patients had cervical intraepithelial neoplasia (CIN) grades 1 to 3 and early invasive cervical carcinoma (ICC). Our objective was to compare anti-α-galactosyl antibody levels among them and with those of normal controls. High levels of anti-Gal(α1 → 2)Gal antibodies were detected in 22 % of patients (P