Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling
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- 作者：Kevin Retailleau1 ; 5 ; Fabrice Duprat1 ; 5 ; Malika Arhatte1 ; 5 ; Sanjeev Sumant Ranade2 ; 5 ; Ré ; mi Peyronnet1 ; Joana Raquel Martins1 ; Martine Jodar1 ; Cé ; line Moro1 ; Stefan Offermanns3 ; Yuanyi Feng4 ; Sophie Demolombe1 ; Amanda Patel1 ; 6 ; patel@ipmc.cnrs.fr" class="auth_mail" title="E-mail the corresponding author ; Eric Honoré ; 1 ; 6 ; honore@ipmc.cnrs.fr" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2015
- 出版时间：10 November 2015
- 年：2015
- 卷：13
- 期：6
- 页码：1161-1171
- 全文大小：2465 K
文摘
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Smooth muscle Piezo1 is required for stretch-activated cationic channel activity
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Piezo1 is dispensable for the arterial myogenic tone
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Piezo1 opening has a trophic effect on the arterial wall of small arteries
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Piezo1 activation increases cytosolic calcium and transglutaminase activity