Toxicological analysis and anti-inflammatory effects of essential oil from Piper vicosanum leaves
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- 作者：Dé ; bora Regina Hoff Braita ; Má ; rcia Soares Mattos Vaza ; Juciclé ; ia da Silva Arrigoa ; Luciana Noia Borges de Carvalhoa ; Flá ; vio Henrique Souza de Araú ; job ; Juliana Miron Vanib ; Jonas da Silva Motac ; Claudia Andrea Lima Cardosoc ; Rodrigo Juliano Oliveirab ; Fá ; bio Juliano Negrã ; oa ; Câ ; ndida Aparecida Leite Kassuyaa ; Arielle Cristina Arenaa ; d ; ariellearena@ibb.unesp.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Piperaceae ; Piper vicosanum ; Essential oil ; Acute toxicity ; Genotoxicity ; Inflammation
- 刊名：Regulatory Toxicology and Pharmacology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：73
- 期：3
- 页码：699-705
- 全文大小：364 K
文摘
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The anti-inflammatory effects of the essential oil from P. vicosanum leaves (OPV) were investigated.
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The toxicological potential (acute toxicity and genotoxicity) of the OPV was investigated.
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LD50 of OPV was higher than 2000 mg/kg.
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These results show that OPV has anti-inflammatory potential without causing acute toxicity or genotoxicity.