Metabolic syndrome and peripheral artery disease: Two related conditions

详细信息    查看全文

• 作者：Pilar Á ; ngeles Oriol Toró ; n^a ; ^{paoriol@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Teresa Badí ; a Farr&eacute ; ^a ; Amparo Romaguera Lliso^b ; Jovita Roda Diestro^c
• 关键词：Peripheral artery disease ; Metabolic syndrome ; Primary care
• 刊名：Endocrinología y Nutrición (English Edition)
• 出版年：2016
• 出版时间：June-July 2016
• 年：2016
• 卷：63
• 期：6
• 页码：258-264
• 全文大小：587 K

文摘

To ascertain the prevalence of metabolic syndrome (MS) in patients with peripheral artery disease (PAD) at the Martorell primary care (PC) center. To analyze the differences in comorbidities and cardiovascular risk factors between patients with PAD with and without MS.

Methods

A cross-sectional, descriptive study on patients diagnosed with PAD according to computerized clinical records of the Martorell PC center. Variables collected included age, sex, high blood pressure (HBP), dyslipidemia (DLP), diabetes (DM), smoking, obesity, cardiovascular disease (CVD), erectile dysfunction (ED), renal failure (RF), and oligoalbuminuria. An analysis comparing patients with and without MS was performed.

Results

There were 131 patients diagnosed with PAD, 104 (79%) of whom were male. Sixty-three (48.1%) also had MS. Patients with both PAD and MS had, as compared to those with PAD only, a higher prevalence of HBP (87.3 vs. 60.3%, p: 0.001), DLP (77.8 vs. 60.3%, p: 0.03), DM (69.8 vs. 30.9%, p: <0.001), obesity (25.4 vs. 10.3%, p: 0.03), CVD (42.9 vs. 19.1%, p: 0.004), ED (81.3 vs. 54.3%, p: 0.02), and RF (40.3 vs. 17.9%, p: 0.006).

Conclusion

Patients with both PAD and MS had a higher prevalence of HBP, DLP, DM, and obesity. They also had more cardiovascular events and were significantly associated with pathological conditions highly relevant for cardiovascular prognosis such as erectile dysfunction and chronic kidney disease.