Differential expression of β-tubulin isotypes in different life stages of Parascaris spp after exposure to thiabendazole
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- 作者：Eva Tydé ; na ; Eva.tyden@slu.se" class="auth_mail" title="E-mail the corresponding author ; Moa Skarina ; Mikael Andersson-Frankob ; Matilda Sjö ; bloma ; Johan Hö ; glunda
- 关键词：Parascaris spp ; β-tubulin ; Gene expression ; Life stages ; Embryogenesis ; Thiabendazole
- 刊名：Molecular & Biochemical Parasitology
- 出版年：2016
- 出版时间：January-February 2016
- 年：2016
- 卷：205
- 期：1-2
- 页码：22-28
- 全文大小：1292 K
文摘
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β-tubulin isotype 1 and 2 was differentially expressed at selected life stages.
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Isotype 1 was expressed at all life stages.
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Isotype 2 expression was strong in eggs and very weak in L2/3 and adult worms.
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Each isotype has specific functions during embryogenesis.
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Exposure to TBZ for five days altered β-tubulin gene expression of isotype 1.