The biology of interleukin-27 reveals unique pro- and anti-inflammatory functions in immunity
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- 作者：Samadhi Aparicio-SiegmundAuthor Vitae ; Christoph Garbers ; cgarbers@biochem.uni-kiel.de" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Interleukin-27 ; EBI3 ; p28 ; gp130 ; WSX-1
- 刊名：Cytokine & Growth Factor Reviews
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：26
- 期：5
- 页码：579-586
- 全文大小：708 K
文摘
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IL-27 has unique pro- and anti-inflammatory properties.
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IL-27 is involved in T cell differentiation, inflammation and infection.
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IL-27 shows overlapping activities and plasticity with IL-6 and IL-35.
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Inhibition of IL-27 might represent a therapeutic approach.