Loss of CRY2 stabilizes c-MYC and enhances cellular transformation
CRY2 can function as a co-factor for the SCF substrate adaptor FBXL3
c-MYC phosphorylated on threonine 58 (T58) interacts with CRY2
SCFFBXL3+CRY2 promotes the ubiquitylation and turnover of c-MYC