Towards patient-specific modeling of mitral valve repair: 3D transesophageal echocardiography-derived parameter estimation
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- 作者：Fan Zhang ; a ; fan.zhang@yale.edu" class="auth_mail" title="E-mail the corresponding author ; Jingjing Kanika ; Tommaso Mansid ; Ingmar Voigtd ; Puneet Sharmad ; Razvan Ioan Ionasecd ; Lakshman Subrahmanyane ; Ben A. Line ; Lissa Sugenge ; David Yuhf ; Dorin Comaniciud ; James Duncana ; b ; c
- 关键词：Mitral valve ; Patient-specific model ; Transesophageal echocardiography ; Finite element biomechanical model ; Mitral valve closure simulation
- 刊名：Medical Image Analysis
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：35
- 期：Complete
- 页码：599-609
- 全文大小：2535 K
文摘
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A semi-automatic framework to build patient-specific models of mitral valve from medical images under user guidance.
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Chordae rest length and material parameters are optimized to calibrate patient-specific models to simulate mitral valve closure consistently with observations from TEE images.
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First study to our knowledge to estimate material parameters of mitral leaflets on humans from TEE images.
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Simulated mitral valve closure from 14 sets of images on 15 patients are compared to the ground truth estimated from TEE images with promising accuracy.