Iron mediated one pot three component synthesis of 3-substituted indoles via aerobic iminium ion formation

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• 作者：Vinay K. Singh ; Laxmi Kant Sharma ; Rana Krishna Pal Singh ; ^{rkp.singh@rediffmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Multicomponent reaction ; Atom economy ; Indoles ; Mannich reaction
• 刊名：Tetrahedron Letters
• 出版年：2016
• 出版时间：20 January 2016
• 年：2016
• 卷：57
• 期：3
• 页码：407-410
• 全文大小：655 K

文摘

An efficient and economical method was developed for the synthesis of 3 substituted indoles by a highly efficient one-pot three component coupling reaction of substituted or unsubstituted benzyl alcohol, N-methyl aniline or pyrrolidine, and indoles or substituted indoles.