Comparative assessment on the prevalence of mutations in the Plasmodium falciparum drug-resistant genes in two different ecotypes of Odisha state, India
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- 作者：Narayani Prasad Kara ; Kshipra Chauhana ; Nutan Nandaa ; Ashwani Kumarb ; Jane M. Carltonc ; Aparup Dasa ; aparup@mrcindia.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：Malaria ; Plasmodium falciparum ; Ecotypes ; Drug resistant genes ; Odisha
- 刊名：Infection, Genetics and Evolution
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：41
- 期：Complete
- 页码：47-55
- 全文大小：624 K
文摘
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Variations in genes conferring drug-resistance in micro eco-epidemiological settings in malaria are not known
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We performed SNP analyses in four different drug-resistant genes in P. falciparum form two different ecotypes
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No significant genetic differentiation between the two ecotypes could be observed
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More cases of genetic linkage between different drug-resistant genes were evident in Riverine-Plain ecosystem