Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti-Bacterial Innate Immunity
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文摘

Atm−/− mice exhibit higher susceptibility to S. pneumoniae

Cells from AT patients and Atm−/− mice elicit diminished inflammasome activation

Loss of ATM impairs NLRC3 and NLRC4 inflammasomes

Loss of ATM impairs inflammasomes via oxidative stress

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