CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells
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- 作者：Rhys J.P. Skelton1 ; 2 ; 3 ; Bevin Brady4 ; Suhail Khoja1 ; 2 ; Debashis Sahoo4 ; James Engel1 ; 2 ; Deevina Arasaratnam3 ; Kholoud K. Saleh1 ; 2 ; Oscar J. Abilez4 ; Peng Zhao1 ; 2 ; Edouard G. Stanley3 ; Andrew G. Elefanty3 ; Murray Kwon5 ; David A. Elliott3 ; Reza Ardehali1 ; 2 ; rardehali@mednet.ucla.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Stem Cell Reports
- 出版年：2016
- 出版时间：12 January 2016
- 年：2016
- 卷：6
- 期：1
- 页码：95-108
- 全文大小：4024 K
文摘
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CD13 and ROR2 separate hESC-derived MIXL1+ mesoderm from MIXL1+ endoderm
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CD13 and ROR2 select for a population of highly enriched pre-cardiac mesoderm
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CD13+/ROR2+ cells derived from hESCs engraft into porcine, but not murine hearts
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CD13+/ROR2+ cells differentiate to all major cardiac lineages in the pig heart