A novel sensing platform for sensitive cholesterol detection by using positively charged gold nanoparticles

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• 作者：Xiangmin Miao^a ; ¹ ; ^{mxm0107@jsnu.edu.cn} ; Zhiyuan Cheng^a ; ^b ; ¹ ; Zongbing Li^a ; Po Wang^b ; ^{wangpo@jsnu.edu.cn}
• 关键词：Cholesterol ; Positively charged gold nanoparticles ; Colorimetric method ; Cetyltrimethyl ammonium bromide
• 刊名：Biochemical Engineering Journal
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：117
• 期：part_PB
• 页码：21-27
• 全文大小：1660 K
• 卷排序：117

文摘

A novel platform: Precipitation of (+)AuNPs was introduced for cholesterol detection for the first time. 4 nm of (+)AuNPs were introduced as signal probe for the first time. Such sensing method more tolerant to the sensing environments because of the stability of (+)AuNPs. A low detection limit of 335 pM was obtained for cholesterol detection. Satisfactory results were obtained for cholesterol detection in serum samples.