Expression of LEF1 in mantle cell lymphoma

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• 作者：Dennis P. O'Malley ; M.D.^a ; ^b ; ^{dennis.omalley@neogenomics.com} ; John P. Lee ; D.O.^c ; Andrew M. Bellizzi ; M.D.^c ; ¹ ; ^{abellizzi@helathcare.uiowa.edu}
• 关键词：Mantle cell lymphoma ; LEF1 ; Chronic lymphocytic leukemia ; Immunohistochemistry ; Diagnosis
• 刊名：Annals of Diagnostic Pathology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：26
• 期：Complete
• 页码：57-59
• 全文大小：828 K
• 卷排序：26

文摘

LEF1 is expressed in up to 5-10% of mantle cell lymphoma This may be a potential pitfall in the differential diagnosis of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and mantle cell lymphoma. LEF1 is expressed in most cases of CLL/SLL and in normal T cells.