Sample size determination for the fluctuation experiment

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• 作者：Qi Zheng ^{qzheng@sph.tamhsc.edu}
• 关键词：Mandelbrot&ndash ; Koch distribution ; Thinned Lea&ndash ; Coulson distribution ; Expected Fisher information ; Plating efficiency
• 刊名：Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：795
• 期：Complete
• 页码：10-14
• 全文大小：486 K
• 卷排序：795

文摘

Sample size determination for the fluctuation experiment so far relies on intuition. The expected Fisher information can be utilized to help determine sample size. Two criteria are suggested to guide the determination of sample size. An explicit formula is given to calculate the required sample size.