Drug-in-cyclodextrin-in-liposomes as a carrier system for volatile essential oil components: Application to anethole
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- 作者：Riham Ghariba ; b ; Lizette Auezovaa ; Catherine Charcossetb ; Hé ; lè ; ne Greige-Gergesa ; greigegeorges@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; hgreige@ul.edu.lb" class="auth_mail" title="E-mail the corresponding author
- 关键词：ANE ; anethole ; ACL ; anethole-in-cyclodextrin-in-liposome ; ACL2 ; double-loaded liposome ; DCL ; drug-in-cyclodextrin-in-liposome ; EE ; encapsulation efficiency ; HP-β-CD ; hydroxypropyl-β-cyclodextrin ; LR ; loading rate ; PdI ; polydispersity index
- 刊名：Food Chemistry
- 出版年：2017
- 出版时间：1 March 2017
- 年：2017
- 卷：218
- 期：Complete
- 页码：365-371
- 全文大小：877 K
文摘
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Drug-in-cyclodextrin-in-liposomes (DCLs) were applied to encapsulate a volatile molecule (anethole).
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The HP-β-CD/anethole complex was loaded into Lipoid S100- and Phospholipon 90H-liposomes.
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DCLs were prepared using single and double loading techniques.
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Nanometric oligolamellar and spherical-shaped vesicles were stable.
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Compared to liposomes, DCL improved the encapsulation and photoprotection of anethole.