We analyzed the role of alloHCT in patients with AML depending on the ratio of mutant to wild-type FLT3 alleles.
According to a predefined cutoff for the allelic ratio for mutant to wild-type FLT3-ITD, patients were grouped into high ratio (HR) and low ratio (LR) FLT3-ITD.
AlloHCT improves EFS and OS in patients with HRFLT3-ITD but only EFS in LRFLT3-ITD AML.