Guillain-Barré syndrome: What have we learnt during one century? A personal historical perspective

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• 作者：A. Uncini ^{uncini@unich.it" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Guillain-Barré ; syndrome ; Acute inflammatory demyelinating neuropathy ; Acute motor axonal neuropathy ; Anti-gangliosides antibodies ; Campylobacter jejuni ; Electrodiagnosis
• 刊名：Revue Neurologique
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：172
• 期：10
• 页码：632-644
• 全文大小：3430 K

文摘

We are approaching the centenary of the first description of Guillain-Barré syndrome. The past 30 years had witnessed an amazing progress in the understanding of the immunological and pathological mechanisms of this disorder. We now recognize that Guillain-Barré syndrome is remarkably heterogeneous and under this umbrella term are several variants and subtypes with distinct clinical, electrophysiological and immunopathological features. This review is a historical journey, through a personal perspective, following the milestones that led to the current substantial knowledge of Guillain-Barré syndrome.