Recurrent obstructive acute pyelonephritis: A rare form of Actinotignum (Actinobaculum) schaalii infection in a HIV-1 infected patient

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• 作者：Anaï ; s Vallet^a ; Nicolas Noë ; l^a ; ^b ; ^c ; ^d ; ^{nicolas.noel@aphp.fr} ; Rachid Bahi^e ; Elina Teicher^a ; Yann Quertainmont^a ; Jean-Franç ; ois Delfraissy^a ; ^b ; ^c ; ^d ; Sophie Ferlicot^b ; ^f ; Anaï ; s Potron^g ; Cé ; cile Goujard^a ; ^b ; Olivier Lambotte^a ; ^b ; ^c ; ^d
• 关键词：Actinobaculum schaalii ; HIV ; Obstructive urinary tract infection ; Kidney stones
• 刊名：Anaerobe
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：43
• 期：Complete
• 页码：75-77
• 全文大小：1380 K
• 卷排序：43

文摘

Actinobaculum schaalii is a rarely reported, anaerobic, Gram-positive bacterium which role as uropathogen is emerging. We report here the case of a 47 year old HIV-1 infected woman presented with five recurrent episodes of obstructive pyelonephritis in the context of multiple renal stones. No bacteria was found until the fifth episode, during which prolonged urinary cultures as well as 16S rDNA sequencing allowed the diagnosis of A. schaalii infection. She had developed a life-threatening condition with severe renal failure. A right nephrectomy was performed and found that the intrarenal stones were attributed to the antiretroviral therapy. The renal parenchyma corresponded to an end-stage renal disease with chronic pyelonephritis without abcesses or granules. The situation improved after six months of amoxicillin therapy.