At depths where the subducting slab interacts with the mantle wedge, along-arc variation in slab seismicity is a fundamental characteristic, with patches of abundant seismicity separated by low seismicity zones. The largest most numerous patch, at 150-220 km depth, underlies a pronounced low Qp zone in the mantle wedge, which is associated with the rhyolite-dominant Taupo caldera. Extensive melt in the region of low Qp requires high H2O flux from the underlying slab. The abundant Taupo seismicity suggests a correlation between melt production and regions of earthquake fracture permeability following embrittlement which promote migration of dehydration fluid. The hydration history of the incoming slab may be a key factor in producing variations in dehydration and intraslab fluid migration. Broader, extensive outer-rise yielding and hydration may have occurred near the approach of the re-entrant Hikurangi Plateau, forming the slab section that currently has high seismicity. Slab seismicity deepens from 240 to 330 km along-arc as the subduction rate increases from <20 to >40 mm/yr. The southwestern slab seismicity is bounded by an unusually narrow zone with 110-km depth extent. This is inferred to be a dehydration front related to heating at a slab edge that is located 70 km further southwest.