Non-neural and cardiac differentiating properties of Tbx6-expressing mouse embryonic stem cells
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- 作者：Yoshiteru Yano n145277g@yokohama-cu.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Naoya Iimura n135351g@yokohama-cu.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Nobuhiko Kojima nobuhiko@yokohama-cu.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hideho Uchiyama ; hideho@yokohama-cu.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：T-box ; Neural differentiation ; Heart development ; ES cells ; Mesodermal differentiation
- 刊名：Regenerative Therapy
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：3
- 期：Complete
- 页码：1-6
- 全文大小：1788 K
文摘
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Tbx6 expression in mouse ES cells (mESCs) inhibited neural differentiation.
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Tbx6 expression in mESCs increased cardiac muscle synergistically with wnt inhibitor.
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Tbx6 expression increased atrial myosin light chains over ventricular chains.