Endocytic regulation of cytokine receptor signaling

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• 作者：Jaroslaw Cendrowski¹Author Vitae ; Agnieszka Mamińska¹Author Vitae ; Marta Miaczynska ; ^{miaczynska@iimcb.gov.pl}Author Vitae
• 关键词：CIE ; clathrin-independent endocytosis ; CME ; clathrin-mediated endocytosis ; DRM ; detergent-resistant microdomains ; EGFR ; epidermal growth factor receptor ; GPI-AP ; glycosylphosphatidylinositol-anchored proteins ; IFN ; interferon ; IFNAR ; type I interferon receptor ; IFNGR ; type II interferon receptor ; IFNR ; interferon receptor ; IL ; interleukin ; ILR ; interleukin receptor ; ILV ; intraluminal vesicle ; JNK ; c-Jun N-terminal kinase ; LTβR ; lymphotoxin β receptor ; MVB ; multivesicular body ; MβCD ; methyl-β-cyc
• 刊名：Cytokine & Growth Factor Reviews
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：32
• 期：Complete
• 页码：63-73
• 全文大小：1161 K
• 卷排序：32

文摘

Endocytosis regulates signaling of plasma membrane receptors. Cytokine receptors can be internalized by various mechanisms. Cytokine receptors can use endosomes as signaling platforms. The effects of endocytosis on signaling output are known for a few cytokine receptors.