Stiffness of polyelectrolyte multilayer film influences endothelial function of endothelial cell monolayer

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• 作者：Hao Chang^a ; He Zhang^a ; Mi Hu^a ; Jia-yan Chen^a ; Bo-chao Li^a ; Ke-feng Ren^a ; ^{renkf@zju.edu.cn} ; M.Cristina L. Martins^b ; ^c ; ^d ; Má ; rio A. Barbosa^c ; ^d ; Jian Ji^a ; ^{jijian@zju.edu.cn}
• 关键词：Endothelial cell ; Endothelial function ; Substrate stiffness ; Polyelectrolyte multilayer films ; Vascular endothelial growth factor
• 刊名：Colloids and Surfaces B: Biointerfaces
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：149
• 期：Complete
• 页码：379-387
• 全文大小：3631 K
• 卷排序：149

文摘

VEGF-bound (PLL/HA) films with controlled stiffness are constructed. Comparable EC monolayers are formed on both soft and stiff films. Endothelial function displays a negatively correlation with substrate stiffness.